Gene transcription and ionizing radiation: methods and compositions
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United States of America Patent
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May 9, 2006
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app pub date -
Dec 5, 2000
filing date -
Dec 20, 1990
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Expired
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Abstract
The present invention provides a DNA molecule comprising a radiation responsive enhancer-promoter operatively linked to an encoding region that encodes at least one polypeptide. An encoding region can comprise a single encoding sequence for a polypeptide or two or more encoding sequences encoding DNA binding, activation or repression domains of a transcription factor. Processes for regulating polypeptide expression and inhibiting tumor growth using such DNA molecules are also provided.
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