RECOMBINANT CONSTRUCTS ENCODING T CELL RECEPTORS SPECIFIC FOR HUMAN HLA-RESTRICTED TUMOR ANTIGENS
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United States of America Patent
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Issued Date -
Jul 5, 2001
app pub date -
Mar 5, 1997
filing date -
Mar 5, 1996
priority date (Note) -
Abandoned
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Abstract
Methods are described to obtain nucleic acid molecules that encode T cell receptors and their derivatives that are human HLA-restricted and which are specific for tumor-associated antigens found in human tumors. These nucleic acids are useful in preparing recombinant cells for diagnosis and therapy of human tumors.
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