Wet granulation formulation for bisphosphonic acids
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United States of America Patent
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app pub date -
Feb 15, 2001
filing date -
Jun 18, 1998
priority date (Note) -
Abandoned
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Abstract
Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
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