SYSTEM FOR TISSUE-RESTRICTED GENE RECOMBINATION
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United States of America Patent
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Issued Date -
Jul 12, 2001
app pub date -
Jun 25, 1998
filing date -
Jun 25, 1998
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods and compositions for tissue-restricted gene recombination. In particular, the present invention provides methods and compositions for tissue-restricted gene recombination in post-mitotic cells. The present invention further provides methods for gene recombination in post-mitotic cells comprising the delivery of a Cre recombinase to the target tissue to facilitate recombination in a desired target nucleic acid.
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