Apparatus and method for spotting a substrate
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United States of America Patent
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-
Oct 22, 2002
Grant Date -
Aug 2, 2001
app pub date -
Mar 20, 2001
filing date -
Mar 15, 1999
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention provides a method and apparatus for dispensing a small volume of a selected liquid, such as a biological sample or reagent, onto a substrate. The device includes a tube adapted to contain the liquid. An elongate fiber is disposed within the tube for axial movement therein between raised and lowered positions. Upon shifting or oscillating the fiber between its raised and lowered positions, a liquid spot can be formed at a selected position on the substrate. The device is readily adaptable for the production of micro-arrays having a great number of individual spots.
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