Combinations of PKC inhibitors and therapeutic agents for treating cancers
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United States of America Patent
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Sep 3, 2002
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app pub date -
Aug 20, 1998
filing date -
Feb 20, 1996
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Abstract
This invention provides methods for screening a modulating agent which when combined with antitumor therapeutic agent increases apoptosis in tumor cells. This invention also provides methods for screening antitumor therapeutic agents suitable for combination therapy with a protein kinase C inhibitors capable of potentiating apoptosis in tumor cells. This invention further provides different combination therapies comprising the specific protein kinase C inhibitors and the antitumor therapeutic agents.
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