Method of promoting bone growth with hyaluronic acid and growth factors
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United States of America Patent
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Mar 9, 2004
Grant Date -
Aug 16, 2001
app pub date -
Apr 3, 2001
filing date -
Mar 5, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at an intra-articular site of desired bone growth for a period of time sufficient to promote the bone growth. Preferably hyaluronic acid is used in a composition range of 0.1-4% by weight and preferred growth factor is bFGF, present in a concentration range of about 10.sup.-6 to 100 mg/ml.
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