Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
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United States of America Patent
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Mar 9, 2004
Grant Date -
Aug 23, 2001
app pub date -
Jan 17, 2001
filing date -
Jan 19, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Benzoylguanidines of the formula (I) ##STR1## in which R1 to R4 have the meanings given in the specification and claims are suitable as antiarrhythmic medicaments having a cardioprotective component for infarct prophylaxis and infarct treatment and for the treatment of angina pectoris. The compounds of the invention also preventively inhibit the pathophysiological processes in the formation of ischemically induced damage, in particular in the triggering of ischemically induced cardiac arrhythmias.
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