Method of treating cancer using dithiocarbamate derivatives
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United States of America Patent
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Apr 15, 2003
Grant Date -
Aug 23, 2001
app pub date -
Dec 12, 2000
filing date -
Sep 8, 1998
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Abstract
Dithiocarbamate, particularly tetraethylthiuram disulfide, and thiocarbamate anions strongly inhibit the growth of cancer cells of a variety of cell types. Such inhibitory effect is enhanced by heavy metal ions such as copper ions, cytokines and ceruloplasmin. A method is presented for using tetraethylthiuram disulfide to reduce tumor growth, and to potentiate the effect of other anticancer agents.
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