Preparation of opiates
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United States of America Patent
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-
N/A
Issued Date -
Aug 30, 2001
app pub date -
Apr 17, 2001
filing date -
Mar 17, 1998
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
A novel process for the preparation of codeinone and analogues thereof comprising the oxidation of a compound of formula, 1 or a salt thereof, wherein R.sup.1 is lower alkyl or a group 2 wherein R.sup.4 is lower alkyl, lower alkyl substituted by halogen or phenyl, phenyl or substituted phenyl; and R.sup.2 is lower alkyl, allyl or lower alkyl substituted by cycloalkyl, characterised in that the oxidation is carried out in an acidic environment is disclosed.
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