
US Patent Application No: 2001/0020,004
Number of patents in Portfolio can not be more than 2000
Analogs of human basic fibroblast growth factor
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Sep 6, 2001
Publication date -
Apr 5, 2001
filing date -
09/826,210
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Abstract
The present invention relates to novel muteins of human basic fibroblast growth factor with superagonist properties. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of said nucleic acid sequences and the production of said muteins. Also disclosed are methods for stimulating cell division, treating a wound, treating ischemia, treating heart disease, treating neural injury, treating peripheral vascular disease, treating a gastric ulcer and treating a duodenal ulcer.
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