Anti-parasitic helminth macrophage migration inhibitory factor antibodies and uses thereof
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United States of America Patent
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Sep 24, 2002
Grant Date -
Sep 13, 2001
app pub date -
Jan 30, 2001
filing date -
Nov 16, 1995
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Abstract
The present invention relates to parasitic helminth macrophage migration inhibitory factor (MIF) proteins; to parasitic helminth MIF nucleic acid molecules, including those that encode such MIF proteins; to antibodies raised against such MIF proteins; and to compounds that inhibit parasitic helminth MIF activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.
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