Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers
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United States of America Patent
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Jan 1, 2008
Grant Date -
Sep 20, 2001
app pub date -
May 7, 1998
filing date -
May 23, 1997
priority date (Note) -
Expired
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Abstract
This invention pertains to the general field of chemical and biological assays which employ electrochemiluminscence (ECL), also referred to as electrogenerated chemiluminescence. More particularly, the present invention pertains to certain classes of chemical moieties which strongly quench ECL, and the use of these ECL quenchers in combination with ECL labels, for example, in ECL assay methods which employ an ECL quencher and an ECL label. One class of such quenching moieties are those which comprise at least one benzene moiety. Sub-classes of such quenching moieties are those which comprise at least one phenol moiety, quinone moiety, benzene carboxylic acid, and/or benzene carboxylate moiety.
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