Novel complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex
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app pub date -
Jun 15, 2001
filing date -
Mar 12, 1999
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Abandoned
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Abstract
The present invention provides a novel complex of hK2 and PI-6 and methods of using the novel complex. The novel complexes of hK2 and PI-6 of the present invention exist at an elevated level in prostate cancer tissues. Therefore, the hK2-PI6 complexes of the present invention may be used as a serum marker for detecting prostate cancer. They may also be used as an immunohistological marker to detect prostate cancer tissues. In accordance with the present invention, the hK2-PI6 complexes of the present invention may be detected in patient tissue samples by immunohistochemical and/or in patient fluid samples by in vitro immunoassay procedures. Diagnostic kits and diagnostic methods for detecting the existence of prostate cancer are also provided.
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Patent Owner(s)
Patent Owner | Address | |
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BECKMAN COULTER INC (FORMERLY BECKMAN INSTRUMENTS INC ) | ATTN M KIVINSKI LEGAL DEPT A-42-C 4300 N HARBOR BOULEVARD FULLERTON CA 92834 |
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Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Mikolajczyk, Stephen D | San Diego, CA | 21 | 111 |
Saedi, Mohammad S | San Diego, CA | 4 | 7 |
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Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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