Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation
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United States of America Patent
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N/A
Issued Date -
Oct 25, 2001
app pub date -
Apr 16, 2001
filing date -
Oct 4, 1999
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Provided are vaccines, methods of making the vaccines and methods for administering the vaccines for immunotherapy of an individual bearing, or at risk for developing, solid nonlymphoid tumor. The vaccine comprises an immunotherapeutic composition and tumor-associated antigen, and may further comprise one or more of an immunomodulator or a pharmaceutically acceptable carrier. A method of immunotherapy of an individual comprises administering to the individual an amount of the vaccine effective to suppress a TH2 response, and to induce a TH1 response against solid nonlymphoid tumor, in an individual having a TH2/TH1 imbalance.
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