Embolic compositions
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United States of America Patent
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Jan 13, 2004
Grant Date -
Nov 1, 2001
app pub date -
Mar 13, 2001
filing date -
Mar 13, 2000
priority date (Note) -
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Abstract
Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.
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