Methods and apparatus for high throughput plate to plate or plate to membrane transfer
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United States of America Patent
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Sep 30, 2003
Issued Date -
N/A
app pub date -
Jul 6, 2001
filing date -
Apr 6, 1998
priority date (Note) -
Expired
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Abstract
Techniques for high throughput parallel separation, filtration and plate-to-plate transfer are described. Cells, proteins, chemical compounds and the like are being developed in multi-well, small volume well plates, such as 1536-well plates having wells of a volume on the order of 1 .mu.l. A mechanism for clamping such plates together so that the wells will be aligned allows rapid separation or transfer by simply centrifuging the assembly. A membrane may be clamped between the plates. Alternatively, a membrane may replace one of the plates. Centrifuge dependent and independent designs are described.
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