US Patent Application No: 2001/0038,851

Number of patents in Portfolio can not be more than 2000

Therapeutic liposome composition and method of preparation

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Abstract

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Reagents for use in preparing a therapeutic liposome composition sensitized to a target cell are described. The reagents include a liposomal composition composed of pre-formed liposomes having an entrapped therapeutic agent and a plurality of targeting conjugates composed of a lipid, a hydrophilic polymer and a targeting ligand. The therapeutic, target-cell sensitized liposome composition is formed by incubating the liposomal composition with a selected conjugate.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ALZA CORPORATIONPALO ALTO, CA438

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Theresa M Edmonton, CA 21 867
Martin, Francis J San Francisco, US 73 3002
Uster, Paul Tracy, US 9 216
Zalipsky, Samuel Redwood City, US 68 1310

Cited Art Landscape

Patent Info (Count) # Cites Year
 
DADE BEHRING MARBURG GMBH (1)
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The Regents of the University of California (1)
* 5,985,852 Inhibition of selectin binding 28 1999
 
BAXTER INTERNATIONAL INC. (1)
* 5,603,872 Method of binding recognizing substances to liposomes 26 1994
 
ALZA CORPORATION (1)
* 6,120,798 Liposome-entrapped polynucleotide composition and method 24 1998
 
LIPOSOME TECHNOLOGY, INC. A CORP. OF DELAWARE (2)
* 5,013,556 Liposomes with enhanced circulation time 649 1989
* 5,395,619 Lipid-polymer conjugates and liposomes 126 1993
 
Sequus Pharmaceuticals, Inc. (3)
* 5,631,018 Lipid-polymer conjugates and liposomes 104 1994
* 5,620,689 Liposomes for treatment of B-cell and T-cell disorders 97 1995
* 5,891,468 Fusogenic liposome compositions and method 74 1997
 
North Carolina State University (1)
* 4,913,902 Purification by affinity binding to liposomes 12 1987
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ABEONA THERAPEUTICS INC. (1)
* 2012/0231,069 Targeted Nanocarrier Systems for Delivery of Actives Across Biological Membranes 0 2012
 
ALZA CORPORATION (2)
* 2005/0191,344 Liposome composition for delivery of therapeutic agents 7 2005
* 2006/0246,126 Therapeutic liposome composition and method of preparation 2 2006
 
RAMOT AT TEL-AVIV UNIVERSITY LTD. (1)
* 2012/0129,916 CELL-TARGETING NANOPARTICLES COMPRISING POLYNUCLEOTIDE AGENTS AND USES THEREOF 0 2010
 
MEBIOPHARM CO., LTD. (2)
7,829,113 Liposome compositions 3 2006
8,758,810 Liposome compositions 6 2010
 
THE OHIO STATE UNIVERSITY (1)
* 2013/0315,937 LIPID NANOPARTICLE COMPOSITIONS FOR ANTISENSE OLIGONUCLEOTIDES DELIVERY 0 2013
 
MEDIGENE AG (1)
* 2005/0232,984 Non-vesicular cationic lipid formulations 0 2005
 
SibTech, Inc. (4)
* 2003/0059,461 Molecular delivery vehicle for delivery of selected compounds to targets 18 2001
7,355,019 Cysteine-containing peptide tag for site-specific conjugation of proteins 8 2005
* 2005/0221,431 Cysteine-containing peptide tag for site-specific conjugation of proteins 7 2005
7,807,778 Cysteine-containing peptide tag for site-specific conjugation of proteins 0 2008
 
CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (6)
* 7,824,709 Lipophilic drug delivery vehicle and methods of use thereof 4 2004
* 2004/0229,794 Lipophilic drug delivery vehicle and methods of use thereof 12 2004
8,268,796 Lipophilic nucleic acid delivery vehicle and methods of use thereof 2 2009
8,268,357 Processes for the preparation of lipophilic drug delivery vehicles 2 2010
8,821,939 Bioactive agent delivery particles 0 2012
9,107,826 Lipophilic drug delivery vehicle and methods of use thereof 0 2013
 
YUNG SHIN PHARMACEUTICAL IND. CO., LTD. (1)
* 2005/0209,252 Cancer treatment 0 2005
 
G. Gaslini Children's Hospital (2)
* 7,479,483 Tumor-targeted drug delivery systems and uses thereof 5 2004
* 2004/0258,747 Tumor-targeted drug delivery systems and uses thereof 6 2004
 
MEDIVAS, LLC (3)
8,652,504 Solid polymer delivery compositions and methods for use thereof 0 2006
* 2007/0282,011 Biodegradable water soluble polymers 2 2007
9,102,830 Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use 0 2013
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (6)
7,361,640 Stable lipid-comprising drug delivery complexes and methods for their production 6 2003
* 2003/0212,031 Stable lipid-comprising durg delivery complexesand methods for their production 4 2003
7,335,509 Stable lipid-comprising drug delivery complexes and methods for their production 9 2004
7,655,468 Stable lipid-comprising drug delivery complexes and methods for their production 2 2007
7,993,672 Stable lipid-comprising drug delivery complexes and methods for their production 1 2009
8,771,728 Stable lipid-comprising drug delivery complexes and methods for their production 7 2012
 
The Penn State Research Foundation (3)
* 9,107,947 Anti-cancer compositions and methods 0 2014
* 2014/0212,475 ANTI-CANCER COMPOSITIONS AND METHODS 0 2014
9,439,887 Anti-cancer compositions and methods 0 2015
* Cited By Examiner