Method for pulmonary and oral delivery of pharmaceuticals

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6616914
APP PUB NO 20010041190A1
SERIAL NO

09907393

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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In a powder formulation for use in a dry powder inhaler, a pharmaceutical acts as its own carrier, so that use of lactose or other excipients are not needed. The dry powder formulation has a single active pharmaceutical compound having two major populations in particle size distribution: microfine particles of the active pharmaceutical, of 1-10 microns in diameter, and larger carrier particles, also of the active pharmaceutical compound. The carrier particles provide a long acting, delayed onset, and optionally therapeutic effect via the GI tract, while the microfine particles provide a fast onset effect via the lung.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MICRODOSE THERAPEUTX, INC.MONMOUTH JUNCTION, NJ56

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Schultz, Robert San Diego, CA 47 1169
Ward, Gary San Diego, CA 9 158

Cited Art Landscape

Patent Info (Count) # Cites Year
 
ARADIGM CORPORATION (1)
* 6167880 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 73 1999
 
AMGEN INC. (1)
* 2001/0006,939 SECRETORY LEUKOCYTE PROTEASE INHIBITOR DRY POWDER PHARMACEUTICAL COMPOSITIONS 11 1997
 
KING PHARMACEUTICALS, INC., A TENNESSEE CORPORATION (1)
5260306 Inhalation pharmaceuticals 151 1991
 
THE PENN STATE RESEARCH FOUNDATION (1)
5874064 Aerodynamically light particles for pulmonary drug delivery 292 1996
 
ASTRAZENECA AB (1)
5518998 Therapeutic preparation for inhalation 166 1994
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Norton Healthcare Limited (6)
* 8273331 Inhalation compositions 0 2003
* 2006/0292,083 Inhalation compositions with high drug ratios 5 2003
* 2005/0158,248 Method of preparing dry powder inhalation compositions 6 2003
* 2004/0258,626 Inhalation compositions 5 2003
8075873 Method of preparing dry powder inhalation compositions 0 2009
* 2009/0264,389 Method of preparing dry powder inhalation compositions 2 2009
 
INNOVATA BIOMED LIMITED (8)
7219665 Delivery device 31 2000
7464704 Medicament delivery assembly 16 2002
8851069 Inhaler 0 2005
8511302 Dose counter mechanisms for medicament delivery devices 1 2005
7571723 Delivery device 20 2007
7571724 Delivery device 19 2007
8800550 Medicament delivery assembly 0 2008
8205614 Delivery device 2 2009
 
MICRODOSE THERAPEUTX, INC. (2)
* 2005/0147,566 Site specific delivery of co-administered drugs via inhalation 16 2004
8991390 Inhalation device and method 0 2011
 
HALE BIOPHARMA VENTURES, LLC (5)
* 2008/0279,784 NASAL ADMINISTRATION OF BENZODIAZEPINES 9 2008
* 8530463 Multimodal particulate formulations 7 2008
* 2009/0130,216 MULTIMODAL PARTICULATE FORMULATIONS 14 2008
* 2009/0258,865 ADMINISTRATION OF BENZODIAZEPINE COMPOSITIONS 10 2009
9763876 Administration of benzodiazepine compositions 0 2014
 
Hale Biopharma Ventures LLC (1)
8895546 Administration of benzodiazepine compositions 1 2012
* Cited By Examiner