Triazospiro compounds having nociceptin receptor affinity
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United States of America Patent
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Feb 3, 2004
Grant Date -
Nov 15, 2001
app pub date -
Dec 6, 2000
filing date -
Dec 6, 1999
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Abstract
Disclosed are compounds of the formula (I) ##STR1## wherein A, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and X.sub.1 are as disclosed herein. The compounds have affinity for the ORL1 receptor and are useful in the treatment of chronic and acute pain.
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