Apparatus and method for treatment of vascular restenosis by electroporation
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United States of America Patent
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Issued Date -
Nov 22, 2001
app pub date -
May 4, 2001
filing date -
May 10, 2000
priority date (Note) -
Abandoned
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Abstract
An apparatus and a method for reducing restenosis rate after balloon angioplasty is provided. The apparatus comprises a high voltage pulse generator and an intravascular catheter with electrodes adapted for delivery of electrical pulses to the media and adventitia of the treated segment of an artery. The amplitude, duration and number of the electrical pulses applied to the artery wall are sufficient to significantly deplete the population of smooth muscle cells, exuberant proliferation of which causes restenosis. To avoid possible fibrillation, the electric pulses are delivered during periods of depolarized state of myocardium.
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