Antioxidant enhancement of therapy for hyperproliferative conditions

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United States of America Patent

PATENT NO 7071158
APP PUB NO 20010049349A1
SERIAL NO

09779086

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method to enhance the cytotoxic activity of an antineoplastic drug comprising administering an effective amount of the antineoplastic drug to a host exhibiting abnormal cell proliferation in combination with an effective cytotoxicity-increasing amount of an antioxidant. The invention also includes a method to decrease the toxicity to an antineoplastic agent or increase the therapeutic index of an antineoplastic agent administered for the treatment of a solid growth of abnormally proliferating cells, comprising administering an antioxidant prior to, with, or following the antineoplastic treatment.

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Patent Owner(s)

  • SALUTRIA PHARMACEUTICALS LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beauchamp, R Daniel Nashville, TN 5 27
Chinery, Rebecca Nashville, TN 1 19
Coffey, Robert J Woodside, CA 2 33
Medford, Russell M Atlanta, GA 19 337
Wadzinski, Brian E Nashville, TN 1 19

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