Tissue formation by injecting a cell-polymeric solution that gels in vivo

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United States of America Patent

PATENT NO 6730298
SERIAL NO

09008945

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Abstract

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Slowly polymerizing polysaccharide hydrogels have been demonstrated to be useful as a means of delivering large numbers of isolated cells via injection. The gels promote engraftment and provide three dimensional templates for new cell growth. The resulting tissue is similar in composition and histology to naturally occurring tissue. This method can be used for a variety of reconstructive procedures, including custom molding of cell implants to reconstruct three dimensional tissue defects, as well as implantation of tissues generally.

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Patent Owner(s)

  • CHILDREN'S MEDICAL CENTER CORPORATION;MASSACHUSETTS INSTITUTE OF TECHNOLOGY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Atala, Anthony Weston, MA 161 5495
Griffith-Cima, Linda Lexington, MA 3 352
Paige, Keith T Brookline, MA 4 382
Vacanti, Charles A Lexington, MA 31 2083

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