Pharmaceutical composition for treatment of duchenne muscular dystrophy
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United States of America Patent
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-
Nov 25, 2003
Grant Date -
Dec 27, 2001
app pub date -
Jul 31, 2001
filing date -
May 21, 1999
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A therapeutic pharmaceutical composition for patients of Duchenne muscular dystrophy with entire loss of exon 20 in dystrophin mature mRNA is provided. The composition comprise as an active principle an antisense oligonucleotide consisting of a 20 to 50-nucleotide sequence against exon 19 of the dystrophin pre-mRNA.
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