Media milling

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6604698
APP PUB NO 20020003179A1
SERIAL NO

09852054

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention describes a process for preparing a dispersion of solid particles of a milled substrate in a fluid carrier comprising the steps of (a) providing a plurality of large size milling media to the milling chamber of a media mill and forming a depth filter therefrom on an exit screen or separator in the milling chamber; (b) adding to said milling chamber a plurality of small size milling media optionally containing additional large size milling media, a conglomerate of a solid substance comprising a substrate to be milled and optionally one or more than one surface active substance, and a fluid carrier; (c) milling said conglomerate in said milling chamber to produce very small milled substrate product particles; and (d) separating said milled substrate particles suspended in said fluid carrier from the media through said depth filter; wherein the exit screen comprises openings of size S.sub.0 ; the large size media have a size distribution S.sub.1 of which all are larger than S.sub.0 ; the small size media have a size distribution S.sub.2 which are smaller than S.sub.0 ; the very small milled substrate particles have a size distribution S.sub.3 and are smaller than all of the small media; and the large size media and the small size media are essentially retained in the milling chamber.

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Patent Owner(s)

  • JAGOTEC AG;PAUL ROYALTY FUND, L.P.;RTP PHARMA INC.

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pace, Gary W Raleigh, NC 27 1072
Snow, Robert A West Chester, PA 39 1156
Verhoff, Frank H Cincinnati, OH 1 98

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