METHOD FOR THE TREATMENT OF STAPHYLOCOCCAL DISEASE
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United States of America Patent
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Issued Date -
Jan 17, 2002
app pub date -
Jul 21, 1998
filing date -
Jul 23, 1997
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Abstract
Lysostaphin is demonstrated to be a powerful anti-staphylococcal agent suitable for parenteral administration to mammals including humans. Low dosages, on the order of 0.5 - 45 mg/kg/day are sufficient to eradicate most staphylococcal infections. Lysostaphin is also effective against bacteria of this type which have developed resistance to conventional antibiotics such as penicillins and vancomycin. Lysostaphin analogues, such as variants and related enzymes, show similar activity.
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