Compositions and methods for improved delivery of hydrophobic agents
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United States of America Patent
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Sep 17, 2002
Grant Date -
Jan 31, 2002
app pub date -
Jul 2, 2001
filing date -
Feb 26, 1999
priority date (Note) -
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Abstract
The present invention relates to triglyceride-free pharmaceutical compositions for delivery of hydrophobic therapeutic agents. Compositions of the present invention include a hydrophobic therapeutic agent and a carrier, where the carrier is formed from a combination of a hydrophilic surfactant and a hydrophobic surfactant. Upon dilution with an aqueous solvent, the composition forms a clear, aqueous dispersion of the surfactants containing the therapeutic agent. The invention also provides methods of treatment with hydrophobic therapeutic agents using these compositions.
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