Importance

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Abstract

A system for removal of skin surface layers and rapid subsurface delivery of fluid therapeutic agents in a treatment to cause neocollagenesis in the dermis to reduce wrinkles and alter the architecture of the dermal layers. The hand-held device has a skin interface with an abrasive that engages and abrades the skin surface as it is translated across a treatment site. The skin interface defines a grooved or undulating surface structure that is intermediate to an arrangement of media inflow ports and the media outflow ports. A preferred working end has a central media outflow port that communicates with a remote negative pressure source via a flexible tube. The skin interface has a plurality of media inflow ports about its periphery. The skin interface is formed of a resilient material such as silicone to allow the working end to flex and atraumatically engage the skin surface as it is translated across a treatment site. In practicing a method of the invention, the system operator (i) actuates a negative pressurization source in fluid communication the media outflow port; (ii) translates the abrasive skin interface across a treatment site abrade a surfacemost layer; and (iii) thereby creates a negative pressure environment within subsurface layers to very rapidly draw the therapeutic fluid media into the subsurface layers though the skin surface that is denuded by the abrasive architecture of the skin interface.

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First Claim