US Patent Application No: 2002/0019,011

Number of patents in Portfolio can not be more than 2000

Methods for identifying combinations of entities as therapeutics

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Abstract

The invention features a method of screening two-entity or higher order combinations for biological activity using combinational arrays. The method includes the steps of: (a) providing the entities, (b) creating an array of combinations of entities, (c) providing a test element that includes one or more distinct biological moieties, (d) contacting the array of combinations of entities with the test element under conditions that ensure that each entity/test element contacting is segregated from the others, (e) detecting or measuring a property of the test element, and (f) identifying combinations of entities that cause an effect on the property of the test element that is different from the effect of an entity of the combination by itself.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
COMBINATORX, INCORPORATEDCAMBRIDGE, MA0

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borisy, Alexis Boston, MA 37 105
Foley, Michael A Chestnut Hill, MA 37 133
Stockwell, Brent R New York, NY 36 110

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
CANON KABUSHIKI KAISHA (2)
7,419,820 Transfer sheet for transferring biologically active substance to culture plate 2 2004
7,960,168 Biologically active substance transfer sheet, cell culture kit constituted of cell culture plate and biologically active substance transfer sheet, producing method thereof and method for screening cell culture conditions utilizing the same 0 2008
 
SYNERGY BIOSYSTEMS LTD. (1)
7,264,933 Methods to identify biologically active agents and synergistic combinations 0 2004