Stable oral pharmaceutical formulation containing an anti-infective agent and a microorganism
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United States of America Patent
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N/A
Issued Date -
N/A
app pub date -
Aug 23, 2001
filing date -
Mar 27, 1997
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A stable fixed dose oral pharmaceutical formulation is provided. The formulation contains at least one anti-infective agent and at least one susceptible microorganism as active ingredients. At least one of the active ingredients is coated to provide a protective barrier around the active ingredient, the active ingredients being contained in a single pharmaceutical formulation. The formulation may be a tablet, a capsule, or a powder which may be made into a stable liquid. The protective barrier protectis the susceptible micro-organism from the effect of the anti-infective agent to maintain the susceptible micro-organism in a viable form for a period of at least three months. The anti-infective agent can be an antibiotic such as an amoxycillin and the microorganism can be Lactobacillus acidophilus.
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