Compositions and methods for promoting healthy joints
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United States of America Patent
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Issued Date -
Feb 28, 2002
app pub date -
Feb 2, 2001
filing date -
Feb 2, 2000
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A dietary supplement for promoting healthy joints and joint tissues is disclosed. The dietary supplement comprises a member selected from the group consisting of niacinamide, niacin, and mixtures thereof and an antioxidant nutrient. Illustrative antioxidant nutrients include N-acetylcysteine, lipoic acid, coenzyme Q10, vitamin E, carotenoids, and zinc. The dietary supplement supports optimal function and health of joints and joint tissues by interrupting a cascade of events involving reactive oxygen species, cytokines, and poly(ADP-ribose) synthetase, which self-amplifying, positive feed-forward cycle is inversely correlated with joint tissue integrity. A method for promoting healthy joints and joint tissues is also described.
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