C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
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United States of America Patent
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Dec 3, 2002
Grant Date -
Feb 28, 2002
app pub date -
Dec 20, 2000
filing date -
Dec 16, 1996
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Abstract
This invention is directed to novel (N-substituted) indole ICE/ced-3-inhibitor compounds. The invention is also directed to pharmaceutical compositions of such indole compounds, plus the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury.
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