Human zona pellucida protein 3 and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7037663
APP PUB NO 20020028470A1
SERIAL NO

09829073

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a method to determine sperm activity comprising the steps of: (a) contacting an appropriate concentration of human zona pellucida protein 3 with an appropriate amount of sperm under conditions permitting the formation of a complex between the human zona pellucida protein 3 and the sperm; and (b) determining the complex formed. The invention further provides a method to determine sperm activity comprising the steps of (a) contacting an appropriate concentration of human zona pellucida protein 3 with an appropriate amount of sperm under conditions permitting an acrosome reaction to occur; and (b) determining the extent of the acrosome reaction. Finally, this invention provides a diagnosis kit for sperm activity comprising three (3) compartments with (a) an appropriate amount of human zona pellucida protein 3; (b) the reagents used for establishing the conditions for allowing the binding of sperm; and (c) the reagents used for establishing the conditions for allowing an acrosome reaction.

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Patent Owner(s)

  • EASTERN VIRGINIA MEDICAL SCHOOL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dong, Ke-Wen Chesapeake, VA 3 1
Gibbons, William E Norfolk, VA 4 31
Oehninger, Sergio C Norfolk, VA 3 3

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