IMMEDIATELY DISINTEGRABLE MEDICINAL COMPOSITION
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United States of America Patent
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N/A
Issued Date -
Mar 14, 2002
app pub date -
Jun 18, 1999
filing date -
Dec 25, 1996
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The present invention relates to a pharmaceutical composition useful for rapid disintegration, which comprises a sparingly soluble medicament held on a gel-forming water-soluble polymer as a solid dispersion, wherein it contains a salt substance that comprises an alkali and a weak or strong acid and has an endothermic standard enthalpy of solution or heat of solution. Since rapid disintegration of the pharmaceutical composition of the present invention and rapid dissolution of the medicament contained in the preparation can be made in the digestive tracts pH-independently, good bioavailability can be attained.
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