Modified modular PKS with retained scaffold

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United States of America Patent

PATENT NO 6391594
SERIAL NO

08846247

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Abstract

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Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds.

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Patent Owner(s)

Patent OwnerAddress
KOSAN BIOSCIENCES INC3832 BAY CENTER PLACE HAYWARD CA 94545

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashley, Gary Alameda, CA 55 455
Fu, Hong Stanford, CA 103 716
Kao, Camilla M Stanford, CA 14 26
Khosla, Chaitan Stanford, CA 123 1801
McDaniel, Robert Palo Alto, CA 76 851

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