Method for predicting the need for dose reductions in chemotherapy for patients with breast cancer: a potential decision aid for the use of myeloid growth factors

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United States of America Patent

APP PUB NO 20020037493A1
SERIAL NO

09891089

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides provided a method and instrument for predicting the probability of a patient requiring a significant dose reduction in adjuvant chemotherapy for breast cancer and/or predicting whether early treatment with a myeloid growth factor is warranted, by determining the patient's dose-adjusted nadir absolute neutrophil count (ANC) in the first cycle of the chemotherapy schedule, further determining the patient's dose-adjusted percent change in platelet count from day one to the dose-adjusted nadir platelet count in the first cycle of the chemotherapy schedule, and then calculating the probability that the patient will receive a suboptimal chemotherapy dose using the dose-adjusted nadir ANC and dose-adjusted percent change in platelet count.

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Patent Owner(s)

Patent OwnerAddress
NEW ENGLAND MEDICAL CENER HOSPITALS INCNEMCH BOX 817 750 WASHINGTON STREET BOSTON MA 02111

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erban, John Wakefield, MA 1 1
Savvides, Panos Boxford, MA 1 1
Selker, Harry Wellesley, MA 3 2
Terrin, Norma Jamaica Plain, MA 1 1

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