Hemoactive compositions and methods for their manufacture and use
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United States of America Patent
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Mar 16, 2004
Grant Date -
Apr 11, 2002
app pub date -
Jun 10, 1999
filing date -
Jun 10, 1999
priority date (Note) -
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Abstract
Dried hemoactive materials comprise both a cross-linked biologically compatible polymer and a non-cross-linked biologically compatible polymer. The cross-linked polymer is selected to form a hydrogel when exposed to blood. The non-cross-linked polymer is chosen to solubilize relatively rapidly when exposed to blood. The non-cross-linked polymer serves as a binder for holding the materials in desired geometries, such as sheets, pellets, plugs, or the like. Usually, the cross-linked polymer will be present in a particulate or fragmented form. The materials are particularly suitable for hemostasis and drug delivery.
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