Generation and use of signal-plexes to develop specific cell types, tissues and /or organs
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United States of America Patent
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app pub date -
Jul 9, 2001
filing date -
Dec 4, 2000
priority date (Note) -
Abandoned
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Abstract
This invention includes methods and compositions for generating signaling complexes ('Signal-plexes') and the use of Signal-plexes for inducing cell divisions, differentiation and transdifferentiation of cells into specific cell, tissue or organ types which resemble the cells, tissues or organs from which the Signal-plexes were derived. Signal-plexes may be used to induce the development of any specific cells, tissues or organs of the body. Signal-plexes may be derived from any tissue of the body. Signal-plexes may be combined with stem cells or cells having stem cell properties in scaffolds for differentiation into tissue or organs in vitro and or in vivo. The applications of this invention comprise tissue repair, and tissue or organ regeneration. Signal-plexes may be used as pharmaceutical agents; they may be used in humans as well as non-humans.
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