Apparatus for the simultaneous transfer of liquid analytes

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United States of America Patent

APP PUB NO 20020081629A1
SERIAL NO

10025391

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for the rapid screening of analytes, such as potential drug candidates, comprises the steps of applying a plurality of analytes to be screened onto one or more, solid support(s) (61) such that the analytes remain isolated from one another; contacting said analyte-carrying solid support(s) (61) with targets provided in a semi-solid or liquid medium, whereby said analytes are released from the solid support(s) (61) to the targets; and measuring analyte-target interactions. This method allows for the manipulation of thousands of different analytes simultaneously. When the analyte is applied to the solid support (61) it can diffuse thereon so as to produce a concentration gradient and serial dilution of analyte if a dose response curve for a candidate drug is required. The method described can be readily automated.

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TIBOTEC N VNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pauwels, Rudi Wilfried Jan Bonheiden, BE 11 52
Roelant, Christiaan Hubert Simon Leuven, BE 11 81
Van, Acker Koenraad Lodewijk August Temse, BE 11 19

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