Alpha 1-antitrypsin preparation as well as a method for producing the same
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United States of America Patent
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Dec 13, 2005
Grant Date -
Jun 27, 2002
app pub date -
Sep 24, 2001
filing date -
Jun 10, 1997
priority date (Note) -
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Abstract
A native, chromatographically purified α1-AT preparation having a purity of at least 0.7 PU/mg protein and a relative plasma α1-AT activity of at least 120% is disclosed. The ratio of active to inactive α1-AT is higher than in plasma. Furthermore, a method of producing this preparation is disclosed, as well as the use of a carrier material, e.g. an inorganic carrier material such as hydroxylapatite for separating active α1-AT from inactive α1-AT.
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