Highly-mineralized osteogenic sponge compositions, and uses thereof
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United States of America Patent
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Jul 21, 2009
Grant Date -
Jun 27, 2002
app pub date -
Aug 6, 2001
filing date -
Feb 4, 1999
priority date (Note) -
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Abstract
Osteogenic sponge compositions having enhanced osteoinductive properties for use in bone repair are described. The compositions include a quickly resorbable porous carrier, a more slowly resorbed mineral scaffold and an osteogenic factor, preferably a bone morphogenetic protein. The compositions enable increased osteoinductive activity while retaining a reliable scaffold for the formation of new bone at an implant site. Methods for therapeutic use of the compositions are also described.
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