Matrix-free osteogenic devices, implants and methods of use thereof
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United States of America Patent
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Jul 30, 2002
Grant Date -
Jul 11, 2002
app pub date -
Jun 22, 2001
filing date -
Feb 7, 1997
priority date (Note) -
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Abstract
Provided herein are methods for inducing bone formation in a mammal sufficient to fill a defect defining a void, wherein osteogenic protein is provided alone or dispersed in a biocompatible non-rigid, amorphous carrier having no defined surfaces. The methods and devices provide injectable formulations for filling critical size defects, as well as for accelerating the rate and enhancing the quality of bone formation in non-critical size defects.
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