GENETICALLY ENGINEERED CELLS WHICH EXPRESS BONE MORPHOGENETIC PROTEINS
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United States of America Patent
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Issued Date -
Aug 1, 2002
app pub date -
Sep 4, 1998
filing date -
Sep 5, 1997
priority date (Note) -
Abandoned
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Abstract
The present invention describes methods of producing cell lines which express recombinant DNA encoding bone morphogenetic proteins (BMP). The cell lines are capable of being implanted in order to enhance the regeneration of tissues through both autocrine and paracrine effects. The cells may further contain DNA encoding receptor proteins which are able to bind to BMPs or enhance or regulate BMP activity.
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