PROCESS FOR THE SYNTHESIS OF NUCLEIC ACIDS ON A SOLID SUPPORT AND COMPOUNDS WHICH ARE USEFUL IN PARTICULAR AS SOLID SUPPORTS IN THE SAID PROCESS
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United States of America Patent
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app pub date -
May 13, 1998
filing date -
Jul 9, 1993
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Abandoned
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Abstract
The object of the present invention is a process for synthesizing solid phase nucleic acids, characterized in that a mineral or organic polymer, bound by a bivalent hydrocarbon radical to an epoxy or glycol-type group, is used as a solid support, said epoxy or glycol-type group comprising two adjacent saturated carbon atoms on which an OH and a nucleophilic group are substituted. The present invention also pertains to compounds containing an epoxy or glycol-type group as defined above, useful for example as a solid support in a process for solid support nucleic acid synthesis.
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