COMPOSITION COMPRISING ENDOTOXIN NEUTRALIZING PROTEIN AND DERIVATIVES AND USES THEREOF
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United States of America Patent
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Issued Date -
Aug 8, 2002
app pub date -
Jul 2, 1998
filing date -
Jul 2, 1998
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Abstract
The present invention relates to the use of endotoxin neutralizing protein (ENP) and derivatives thereof as stand alone microbial inhibitors or as synergistic enhancers of antibiotics and preservatives. Compositions comprising ENP or alone or in combination with an antibiotic may be used to prevent or treat gram-negative bacterial infections, endotoxemia, septic shock, gram-positive bacterial infections, yeast infections and fungal infections. Compositions comprising ENP alone or in combination with a conventional preservative may be used as antimicrobial preservative in cosmetic or personal care preparations.
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