Novel metalloproteases having thrombospondin domains and nucleic acid compositions encoding the same
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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N/A
Issued Date -
Aug 8, 2002
app pub date -
Feb 16, 2001
filing date -
Feb 18, 2000
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
Novel metalloproteases having thrombospondin domain(s) (MPTS proteins) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including diagnostic applications, therapeutic agent screening applications, as well as therapeutic applications for a variety of different conditions. Also provided are methods of treating disease conditions associated with aggrecanase activity, e.g. conditions characterized by the presence of aggrecan cleavage products, such as rheumatoid- and osteo-arthritis.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- A01N:PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLA....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- C07K:PEPTIDES
- [Classification Symbol]
- [Patents Count]
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