Use of texaphyrins in macrophage-mediated disease
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United States of America Patent
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Issued Date -
Aug 22, 2002
app pub date -
Jan 5, 2001
filing date -
Jul 6, 1998
priority date (Note) -
Abandoned
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Abstract
The present invention provides methods for treating disease of a subject in need thereof by sensitizing the effects of a co-therapeutic agent in macrophages. The method comprises administering a texaphyrin and a co-therapeutic agent to the subject. Texaphyrins are provided for enhancing the cytotoxicity of therapeutic agents in macrophage-mediated disease since texaphyrins have been shown to accumulate in macrophage.
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