Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
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United States of America Patent
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May 22, 2007
Grant Date -
Sep 26, 2002
app pub date -
Jul 23, 2001
filing date -
Jan 24, 2000
priority date (Note) -
Expired
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Abstract
A method for homogeneously assaying biopolymer bonding includes obtaining signals from a test sample before, during and/or after the application of stimulus to the test sample and correlating the signals. The signals, whose magnitude correlate with binding affinity, can be, for example, electrical conductance and/or fluorescent intensity. The stimulus can be, for example, electric voltage and/or laser radiation. Preferably, different types of signals are measured and compared so as to enhance the reliability of the assay.
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