Direct haplotyping using carbon nanotube probes
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United States of America Patent
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Issued Date -
Oct 10, 2002
app pub date -
Sep 12, 2001
filing date -
Sep 11, 2000
priority date (Note) -
Abandoned
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Abstract
A method is described for multiplexed detection of polymorphic sites and direct determination of haplotypes in DNA fragments, DNA, and genomic DNA, using single-walled carbon nanotube (SWNT) atomic force microscopy (AFM) probes. This technique has applications for haplotyping in population-based genetic disease studies and other genomic screening.
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