Controlling protein levels in eucaryotic organisms
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jul 11, 2006
Issued Date -
N/A
app pub date -
Jun 14, 2001
filing date -
Feb 12, 1999
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Method for reducing the level and/or activity of a target protein in a eukaryotic cell via activation of ubiquitination of the target protein wherein the cell is contacted with the compound having a ubiquitination recognition element covalently linked to a target protein binding element. The ubiquitination and recognition element can bind to either the E3 or E2 elements of the ubiquitination system and the target protein binding element is able to bind specifically to the target protein. The target protein binding element has a molecular weight of less than 30,000 and has a binding affinity for the target protein greater than 10.sup.5M.sup.31 1.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully